Powerful Prayers for Deliverance from Enemies That Work

Enemies pop up in life when you least expect them. Maybe it’s a coworker spreading gossip, a neighbor causing trouble, or even someone close betraying your trust. These battles aren’t just physical—they can weigh heavy on your spirit too. That’s where prayer comes in.

The Bible tells us God is our refuge and strength, a very present help in trouble (Psalm 46:1). When you’re facing opposition, lifting your voice to Him can shift things in ways you can’t imagine.

I’ve seen friends pray together over a tough situation—like a family feud—and watch peace break through.

Collective prayer taps into God’s power, bringing protection and victory. Scripture says if we resist the enemy, he’ll flee (James 4:7).

So, don’t face it alone. Grab these prayers and use them whenever you need deliverance from those who stand against you.

Prayer for Deliverance from a Malicious Coworker

Heavenly Father, I come before You seeking deliverance from this coworker stirring up strife. Their words cut deep, and their actions disrupt my peace. You see everything, Lord—nothing is hidden from You. I ask for Your shield around me, guarding my heart and mind from their schemes. Let their plans fall apart, as Psalm 55 says, for You hear the cries of the afflicted. Give me wisdom to navigate this tension and strength to stand firm. Turn their malice into confusion, and let Your favor shine on me instead. I trust You to fight this battle, Lord. Break every chain of conflict they’ve tied around my workplace. I declare Your peace over my day and victory over their attacks, in Jesus’ mighty name. Amen.

Prayer for Deliverance from a Deceitful Friend

Lord God, I bring this friend before You—the one who’s turned against me with lies. My heart hurts from their betrayal, but You’re my rock. Expose their deceit, as You promised in Luke 8:17 that nothing hidden stays that way. Deliver me from their influence and cut every tie that binds me to their falsehoods. Fill me with discernment to see truth clearly. I lean on Your strength to let go of this pain and not repay evil with evil. Protect me from their words and restore my trust in Your timing. I stand on Your Word—greater is He in me than he in the world. I claim freedom from this hurt and victory over their schemes, in Jesus’ name. Amen.

Prayer for Deliverance from a Threatening Neighbor

Father, I lift up this neighbor causing chaos in my life. Their threats and actions unsettle my home, but You are my defender. Surround me with Your angels, Lord, and let no weapon formed against me prosper, like Isaiah 54:17 says. I ask You to soften their heart or remove their power to harm me. Grant me courage to face this without fear and peace that overflows despite their noise. Confound their plans and let Your presence be my fortress. I pray for my family too—keep us safe under Your wings. I declare Your authority over this situation, trusting You to deliver me from their threats. My home is Yours, Lord, and I rest in Your protection, in Jesus’ name. Amen.

Prayer for Deliverance from Spiritual Attacks

Almighty God, I stand before You against these spiritual enemies pressing in. The weight feels heavy, but You’re my deliverer. I put on Your full armor, as Ephesians 6 teaches, and resist every dark force coming against me. Break the chains of fear and confusion they try to bind me with. Let Your light shatter their darkness and Your truth silence their lies. I plead the blood of Jesus over my life—nothing can stand against it. Strengthen my spirit to pray without ceasing and trust Your power. I rebuke every attack in Your name, claiming victory through Christ who overcame. Deliver me, Lord, and set my feet on solid ground. I praise You for the triumph that’s already mine, in Jesus’ name. Amen.

Prayer for Deliverance from a Relentless Family Foe

Lord, I come to You about this family member who won’t let up. Their bitterness tears at our bond, and I’m weary from the fight. You know every wound they’ve caused, Father. I ask for deliverance from their unrelenting anger. Heal what’s broken in them, as You’re the God of restoration. Guard my heart from resentment and give me patience to endure. Your Word in Romans 12 says to bless, not curse, those who persecute me—so I pray blessings over them now. Shift this battle into Your hands, Lord, and free me from its grip. I trust You to bring peace where strife reigns. I declare Your love stronger than their hate, and I claim deliverance today, in Jesus’ name. Amen.

Prayer for Deliverance from Public Slander

Heavenly Father, I cry out to You about those spreading slander against me. Their words sting, tarnishing my name before others. But You’re my vindicator, Lord. Lift me above this storm and silence their false tongues. Psalm 31 says You’re a refuge for the oppressed—be that for me now. Expose their lies and let truth rise up like the sun. I ask for strength to hold my head high and grace to forgive even this. Deliver me from the shame they heap on me, and restore my reputation in Your way. I stand firm in Your promises, knowing no slander can undo Your plans for me. I declare Your justice over this mess and peace over my spirit, in Jesus’ name. Amen.

Prayer for Deliverance from an Overwhelming Adversary

God of power, I face an enemy too big for me alone. Their strength intimidates, but You’re greater still. I run to You, my stronghold, asking for deliverance from their grasp. Your Word in 2 Samuel 22 calls You my rescuer—rescue me now, Lord. Crush their efforts to overwhelm me and scatter their plans like dust. Give me boldness to stand when I want to shrink back. I lean on Your might, not mine, knowing You never lose a battle. Surround me with Your presence and lift this burden off my shoulders. I proclaim Your victory over this giant, trusting You to bring me through. Deliverance is mine because You are mine, in Jesus’ mighty name. Amen.

Final Thoughts

These prayers are tools for anyone facing enemies—big or small. God hears every word and moves when we call. Use them boldly and watch Him work.